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Properties of substance:
TZ
skc-file
Synonyms:
saxitoxin dihydrochloride
Group of substances:
organic
Physical appearance:
white crystals
Empirical formula (Hill's system for organic substances):
C
9
H
1
7
Cl
2
N
7
O
4
Molar/atomic mass: 358.18
Decomposition temperature (°C):
110
CAS №: 35554-08-0
Solubility (g/100 g of solvent):
ethanol
: soluble [
Ref.
]
methanol
: soluble [
Ref.
]
water
: very soluble [
Ref.
]
Dissociation:
pK
BH
+
(1) = 8.5 (25°C, water)
pK
BH
+
(1) = 11.5 (25°C, water)
LD
50
(mg/kg):
0.091 (pigeons, oral)
0.28 (cats, oral)
0.0027 (cats, intravenous)
0.003 (rabbits, intravenous)
0.19 (rats, oral)
0.012 (rats, intravenous)
0.0105 (rats, intraperitoneal)
0.135 (guinea pig, oral)
0.26 (mice, oral)
0.0034 (mice, intravenous)
0.008 (mice, subcutaneous)
0.008 (mice, intraperitoneal)
0.364 (monkeys, oral)
0.18 (dogs, oral)
0.0034 (, intravenous)
0.007 (mens, oral)
0.0057 (mens, )
References:
Bhakuni D.S., Rawat D.S. Bioactive Marine Natural Products, 2005. - pp. 153-156, 161-162
Potential military chemical/biological agents and compounds. - Washington: Departament of the Army, 1990. - pp. 84
Антонов Н.С. Химическое оружие на рубеже двух столетий. - М., 1994. - pp. 116-117 [Russian]
Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 528 [Russian]
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© Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru