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Properties of substance:

5-(3,4,5-trimethoxybenzyl)-2,4-diaminopyrimidine



skc-file

Synonyms:

trimethoprim

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C14H18N4O3

Molar/atomic mass: 290.318

Melting point (°C):

199-203

CAS ¹: 738-70-5

Solubility (g/100 g of solvent):

benzene: 0.0023 (25°C) [Ref.]
benzylic alcohol: 7 (25°C) [Ref.]
chloroform: 1.23 (25°C) [Ref.]
diethyl ether: 0.0042 (25°C) [Ref.]
methanol: 1.53 (25°C) [Ref.]
propylene glycol: 2.48 (25°C) [Ref.]
water: 0.04 (25°C) [Ref.]

Dissociation:

pKBH+ (1) = 6.6 (25°C, water)

LD50 (mg/kg):

7000 (mice, oral)

References:

  1. The Merck Index 11th ed., Merck & Company, 1989. - pp. 1528
  2. Yalkowsky S.H., Yan H., Jain P. Handbook of aqueous solubility data. – 2nd ed. - CRC Press, 2010. - pp. 1019

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru