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Properties of substance:

strychnine



skc-file

Group of substances:

organic

Physical appearance:

colorless rhombic crystals

Empirical formula (Hill's system for organic substances):

C21H22N2O2

Molar/atomic mass: 334.42

Melting point (°C):

282

CAS №: 57-24-9

Solubility (g/100 g of solvent):

acetone: 0.167 (15°C) [Ref.]
amyl alcohol: 0.55 (25°C) [Ref.]
aniline: 20 (20°C) [Ref.]
benzene: 0.77 (20°C) [Ref.]
carbon tetrachloride: 0.158 (20°C) [Ref.]
chloroform: 10.25 (25°C) [Ref.]
diethyl ether: 0.018 (25°C) [Ref.]
diethylamine: 1.7 (20°C) [Ref.]
ethanol: 0.7 (25°C) [Ref.]
ethyl acetate: 0.197 (20°C) [Ref.]
glycerol: 0.25 (15°C) [Ref.]
methanol: 0.49 (25°C) [Ref.]
p-cymene: 0.71 (30°C) [Ref.]
p-cymene: 0.95 (100°C) [Ref.]
petroleum ether: 0.0093 (20°C) [Ref.]
piperidine: 0.7 (20°C) [Ref.]
pyridine: 1.5 (20°C) [Ref.]
pyridine 50% aq.: 2.43 (20°C) [Ref.]
water: 0.016 (25°C) [Ref.]

Numerical data:

Year of discovery: 1818

Density:

1.36 (20°C, g/cm3)

Vapour pressure (Torr):

5 (270°C)

Dissociation:

pKBH+ (1) = 8 (25°C, water)
pKBH+ (2) = 2.3 (25°C, water)

LD50 (mg/kg):

0.5 (cats, oral)
0.33 (cats, intravenous)
0.6 (rabbits, oral)
0.4 (rabbits, intravenous)
2.35-16 (rats, oral)
2 (mice, oral)
0.12 (mice, intravenous)
0.47 (mice, subcutaneous)
0.4 (mice, intramuscular)
0.98 (mice, intraperitoneal)
0.5 (dogs, oral)
0.8 (dogs, intravenous)
0.35 (dogs, subcutaneous)
3 (ducks, oral)
5-120 (mens, oral)

References:

  1. Eason C.T., Ogilvie S. A re-evaluation of potential rodenticides for aerial control of rodents. - 2009. - pp. 10-11
  2. Gupta R.C. Handbook of Toxicology of Chemical Warfare Agents. - Elsevier, 2009. - pp. 199-205
  3. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 812-813
  4. Вредные вещества в промышленности: Справочник для химиков, инженеров и врачей. - 7-е изд., Т.2. - Л.: Химия, 1976. - pp. 569-570 [Russian]
  5. Справочник по растворимости. - Т.1, Кн.2. - М.-Л.: ИАН СССР, 1962. - pp. 1040, 1151, 1284, 1307, 1588 [Russian]
  6. Справочник химика. - Т. 3. - М.-Л.: Химия, 1965. - pp. 103 [Russian]
  7. Химическая энциклопедия. - Т. 4. - М.: Советская энциклопедия, 1995. - pp. 441 [Russian]
  8. Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 530 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru