Main page (Russian) Search in database (English)

Properties of substance:

isoniazid



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C6H7N3O

Molar/atomic mass: 137.139

Melting point (°C):

172

CAS №: 54-85-3

Solubility (g/100 g of solvent):

benzene: practically insoluble [Ref.]
chloroform: 0.1 [Ref.]
diethyl ether: practically insoluble [Ref.]
ethanol: 2 (25°C) [Ref.]
water: 10.71 (20°C) [Ref.]
water: 12.28 (25°C) [Ref.]
water: 20.63 (40°C) [Ref.]

LD50 (mg/kg):

1400 (white rats, oral)
150 (white mice, oral)
1250 (rats, oral)
365 (rats, intravenous)
133 (mice, oral)
149 (mice, intravenous)
50 (dogs, oral)

References:

  1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1105
  2. The Merck Index 11th ed., Merck & Company, 1989. - pp. 816-817
  3. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 267
  4. Полюдек-Фабини Р., Бейрих Т. Органический анализ. - Л.: Химия, 1981. - pp. 305-306 [Russian]
  5. Рубцов М.В., Байчиков А.Г. Синтетические химико-фармацевтические препараты. - М., 1971. - pp. 182-184 [Russian]
  6. Справочник химика. - Т. 6. - Л.: Химия, 1967. - pp. 874-875 [Russian]
  7. Токсикологический вестник. - 2000. - №6. - pp. 46-47 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru