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Properties of substance:

levorphanol tartrate dihydrate



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C21H33NO9

Molar/atomic mass: 443.5

Melting point (°C):

114

Decomposition temperature (°C):

115

Numerical data:

μ-Opioid Receptor Binding (nM): 0.21
κ-Opioid Receptor Binding (nM): 2.3
δ-Opioid Receptor Binding (nM): 4.2

LD50 (mg/kg):

150 (rats, oral)
27 (rats, intravenous)
285 (mice, oral)
32 (mice, intravenous)
46 (dogs, intravenous)

References:

  1. Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 1570-1571
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1171
  3. Problems of Drug Dependence 1991: Proceeding of the 53rd Annual Scientific Meeting The Committee on Problems of Drug Dependence, 1992. - pp. 516
  4. The Merck Index 11th ed., Merck & Company, 1989. - pp. 862
  5. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 142 [Russian]
  6. Рубцов М.В., Байчиков А.Г. Синтетические химико-фармацевтические препараты. - М., 1971 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru