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Properties of substance:

salicylamide

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C7H7NO2

Structural formula as text:

HOC6H4CONH2

Molar/atomic mass: 137.136

Melting point (°C):

141

Solubility (g/100 g of solvent):

1,4-dioxane: 24.8 (25°C) [Ref.]
chloroform: sparingly soluble [Ref.]
diethyl ether: soluble [Ref.]
ethanol: soluble [Ref.]
water: 0.1454 (15°C) [Ref.]
water: 0.21 (20°C) [Ref.]
water: 0.29 (30°C) [Ref.]
water: 0.73 (50°C) [Ref.]

LD50 (mg/kg):

980 (rats, oral)
300 (mice, oral)
313 (mice, intravenous)

References:

  1. Dictionary of organic compounds. - Vol. 3, naphthacarbazole - zygadenine. - М.: ИИЛ, 1949. - pp. 613
  2. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 72
  3. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1851-1852
  4. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 541
  5. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 386-387
  6. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 178 [Russian]
  7. Халецкий А.М. Фармацевтическая химия. - Л.: Медицина, 1966. - pp. 171-172 [Russian]
  8. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 514 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru