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Properties of substance:

4-amino-2-hydroxybenzoic acid

Synonyms:

p-aminosalicylic acid

Group of substances:

organic

Physical appearance:

needles crystals

Empirical formula (Hill's system for organic substances):

C7H7NO3

Structural formula as text:

H2NC6H3(OH)COOH

Molar/atomic mass: 153.135

Melting point (°C):

147

Solubility (g/100 g of solvent):

diethyl ether: sparingly soluble [Ref.]
ethanol: 4.8 (20°C) [Ref.]
water: 0.2 (20°C) [Ref.]

Dissociation:

pKBH+ (1) = 3.5 (20°C, water)
pKa (1) = 3.25 (20°C, water)
pKa (2) = 10 (20°C, water)

LD50 (mg/kg):

3650 (rabbits, oral)
4000 (mice, oral)
4000 (mice, subcutaneous)
4250 (mice, intraperitoneal)

References:

  1. Journal of Physical and Chemical Reference Data. - 2013. - Vol. 42, No. 3. - pp. 033103-138 - 033103-139
  2. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 219
  3. Stahl P.H., Wermuth C.G. Handbook of Pharmaceutical Salts: Properties, Selection, and Use. - Wiley-VCH, 2002. - pp. 304

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru